Filtration for sterility and product recovery
Filtration is a common process in the pharmaceutical and
biotechnology industries. It is used widely to sterilize process gases and
liquids by mechanical separation and to separate product downstream using
ultra-, dia- or nano-filtration. Wherever and however they are used, filtration
systems need to be easy to clean and capable of sterile operation. All our
systems are designed to make sure that contamination is kept out and your
product is as pure as it can be.
We have the expertise to integrate filtration lines into your plant and to
provide the necessary automation, qualification and documentation to meet your
specific needs. Filtration systems can be integrated as required into a variety
of operations including: pre-filtration and sterile filtration, automatic test
benches with integrated CIP and SIP, integrity test inline, solvent exchange by
dia-filtration, or product recovery by nano-filtration.
Cell disruption
Product accumulators within cells that must be distrupted to release their
contents. There are a variety of techniques available to achieve this including
Niro Soavi
homogenizers and other disruption devices. We use our experience to select
the correct equipment and set the necessary process parameters to provide you
with your desired outcome.
Safe separation
After fermentation, separation using centrifuges forms a vital part of
downstream processing for cell separation, product recovery and debris
removal. Our experienced engineering staff will work with you to select
the correct centrifuge type in cooperation with Westfalia Separator for each application and will use
their skill to integrate the separation system seamlessly into the existing
plant.